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Search Results for " j 9 "

20

Compounds

Cat No. Product Name Synonyms Targets
T24189 J9 J-9,J 9
J9 is an inhibitor of Glucocorticoid resistance. J9 reverses Dexamethasone Resistance in T-cell Acute Lymphoblastic Leukemia.
T36949 Niaprazine 5-HT Receptor , Adrenergic Receptor , Histamine Receptor
Niaprazine is a histamine H1-receptor antagonist with marked sedative properties. Niaprazine has antihistamine and antiserotonin activities and can be used for sleep disorder research[1][2]. Niaprazine exhibits a low aff...
TN3222 7-Deacetoxytaxinine J Others
7-Deacetoxytaxinine J is a natural product for research related to life sciences. The catalog number is TN3222 and the CAS number is 18457-45-9.
TN3873 Diosbulbin J Others
Diosbulbin J is a natural product for research related to life sciences. The catalog number is TN3873 and the CAS number is 1187951-06-9.
T69811 AGI25696
AGI-25696 is a MATA2 inhibitor that are useful as therapeutic agents for treating malignancies. AGI-25696 showed in vivo activity in MTAP null tumors. Note: The correct structure of AGI-25696 is CAS#2201065-84-9. Many ve...
T80907 TYVPANASL
TYVPANASL, a nine-amino-acid MHC I-binding epitope from HER2/neu for CD8 T cells, can be utilized in the development of J-LEAPS vaccines [1].
T80906 TYVPANASL TFA
TYVPANASL TFA, a nine-amino-acid MHC I-binding CD8 T-cell epitope derived from HER2/neu, is utilized in the formulation of J-LEAPS vaccines [1].
T37176 Edoxaban impurity 6
Edoxaban impurity 6 is an impurity of Edoxaban. Edoxaban (DU-176) is a selective, potent and orally active factor Xa (FXa) inhibitor with Kis of 0.561 nM and 2.98 nM for free FXa and prothrombinase, respectively. Edoxaba...
T35655 2,6-Dichloropurine-9-β-D-riboside
2,6-Dichloropurine-9-β-D-riboside is a building block.1,2It has been used in the synthesis of photoaffinity probes for nucleotide binding sites in proteins. 1.Wower, J., Hixson, S.S., Sylvers, L.A., et al.Synthesis of 2,...
T35701 FSL-1 TFA
FSL-1 TFA, a toll-like receptor 2/6 (TLR2/6) agonist derived from bacteria, bolsters resistance against experimental HSV-2 infection[1] and stimulates MMP-9 production via the TLR2 and NF-κB/AP-1 signaling pathways in mo...
T36893 4-oxo Withaferin A
4-oxo Withaferin A is a derivative of the steroidal lactone withaferin A that has anticancer activity.1 It is cytotoxic to A2780 ovarian cancer cells and carboplatin-resistant A2780 (A2780/CP70) cells (IC50s = 7.3 and <1...
T38255 Penipurdin A
Penipurdin A is an anthraquinone fungal metabolite originally isolated fromP. purpurogenumthat has antibacterial activity.1,2It is active againstM. tuberculosiswith a MIC value of 25 μg/ml.2 1.Xue, J., Fu, Y., Wu, P., et...
T35762 MC1742
MC1742 is an inhibitor of class I histone deacetylases (HDACs; IC50s = 0.1, 0.11, 0.02, and 0.61 μM for HDAC1, -2, -3, and -8, respectively) and class IIb HDACs (IC50s = 7 and 40 nM for HDAC6 and HDAC10, respectively).1 ...
T37971 12-oxo-13-HOME
12-oxo-13-HOME is an oxylipin derived from linoleic acid .1It is formedviaa 13-HpODE intermediate that is produced by lipoxygenase-mediated metabolism of linoleic acid.2,3,112-oxo-13-HOME has been found in corn and sunfl...
T35504 (±)10-HDHA
(±)10-HDHA is an autoxidation product of docosahexaenoic acid (DHA) in vitro.[1][2] It is also produced from incubations of DHA in rat liver, brain, and intestinal microsomes.[3][4][5] (±)10-HDHA is a potential marker of...
T35647 4-oxo-27-TBDMS Withaferin A
4-oxo-27-TBDMS Withaferin A is a derivative of the steroidal lactone withaferin A that has anticancer activity.1 It is cytotoxic to A2780 ovarian cancer cells (IC50 = 17 μM) but not to carboplatin-resistant A2780 (A2780/...
T36443 (R,R)-CXCR2-IN-2 (R,R)-CXCR2-IN-2
(R,R)-CXCR2-IN-2, a diastereoisomer of CXCR2-IN-2 (compound 68), functions as a brain-penetrant CXCR2 antagonist. It exhibits a pIC50 of 9 in the Tango assay and 6.8 in the HWB Gro-α induced CD11b expression assay[1].
T73399 FTX-6746
receptor gamma (PPARG) durably eradicate tumors in urothelial cancer (UC) animal models. European Journal of Cancer , 2022, 174: S33-S34. https://www.ejcancer.com/article/S0959-8049(22)00889-9/abstract FTX-6746...
T35789 Palmitic acid-1-13C
Palmitic acid-13C is intended for use as an internal standard for the quantification of palmitic acid by GC- or LC-MS. Palmitic acid is a 16-carbon saturated fatty acid. It comprises approximately 25% of human total plas...
T37553 (-)-Mycousnine
(-)-Mycousnine is a microbial metabolite and derivative of usnic acid originally isolated fromM. nawaethat has antibacterial and antifungal activities.1,2It is active against the Gram-positive bacteriaB. subtilis,K. rhiz...
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